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Dilated cardiomyopathy (DCM) is a condition in which the left ventricle, the heart's main pumping chamber, is enlarged (dilated). As the chamber gets bigger, its thick muscular wall stretches, becoming thinner and weaker. This affects the heart's ability to pump enough oxygen-rich blood to the rest of the body.
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LV end-diastolic pressure-volume relations. Stiffnesses at typical operating points are shown as the change in pressure (ΔP) divided by the change in volume (ΔV). See text for discussion. In contrast, in dilated cardiomyopathy, the LV end-diastolic pressure-volume relation is shifted substantially to the right (curve B, Figure 1 ).
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