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Systolic function is conveniently (although not always accurately) measured as the ejection fraction (EF), calculated as stroke volume divided by end-diastolic volume. 1 The LV EF is easily interpreted. The lower limit of normal is ≈50%. The lower the EF is, the greater the reduction in systolic function.
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Diastolic dysfunction occurs when the heart has a hard time relaxing between each beat. This causes restricted blood pumping and increased pressure, which leads to diastolic heart failure (also known as heart failure with preserved ejection fraction, or HFpEF ).
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