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Left ventricular hypertrophy, or LVH, is a term for a heart’s left pumping chamber that has thickened and may not be pumping efficiently. Sometimes problems such as aortic stenosis or high blood pressure overwork the heart muscle. In response to this pressure overload, the inner walls of the heart may respond by getting thicker.
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Schematic LV pressure-volume relationship through 1 cardiac cycle in systolic heart failure (left), a normal control (center), and diastolic heart failure (right). The dominant functional abnormality in systolic heart failure is a decrease in LV contractility, as evidenced by a decrease in the slope of the end-systolic pressure-volume .
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